Faculty of Veterinary Medicine
Bringing innovation and community together to advance animal and human health
On Friday, February 21, 2014 Dr. Michael Murtaugh of the University of Minnesota, will speak to faculty, students and staff about porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV causes a serious disease in pigs, causing highly variable levels of immunity. To better understand the basis for this variation, Dr. Murtaugh and his team have characterized antibody repertoire formation and diversity in the pig, since humoral immunity is an integral component of anti-viral immunity. Although antibody diversity is considered to be virtually limitless, there are substantial individual differences in light and heavy chain gene segment usage, hypersomatic mutation, and response to infection. An explanation of immunoglobulin structures associated with highly protective immune responses will help guide improved vaccine development and provide useful models for other animal species and humans.
In lay terms, tell us about your research and its impact.
What are the three take away messages you want the audience to leave with?
What else are you researching?
Presented on February 21, 2014.