Assistant Professor, Physiology & Pharmacology
Comparative Biology & Experimental Medicine (CBEM)
Member, Hotchkiss Brain Institute
Dr. Trang obtained his BSc (Honours) and PhD degree from Queen’s University. His doctoral training in Pharmacology and Toxicology focused on the effects of opioid analgesic drugs in the brain and spinal cord. He then pursued training as a CIHR Postdoctoral Fellow at the Hospital for Sick Children in Toronto, where he expanded his area of expertise into the study of chronic pain. Dr. Trang is an Assistant Professor in the Department of Comparative Biology and Experimental Medicine (Faculty of Veterinary Medicine) and the Department of Physiology and Pharmacology (Faculty of Medicine). He is also a member of the Hotchkiss Brain Institute.
How does our body tell us something is painful? Why do certain people go on to develop chronic pain whereas others, with apparently similar disorders or injuries, do not? And why is pain so difficult to treat? To begin to unravel the great paradox of pain, our research focuses on discovering the fundamental molecules and processes involved in chronic pain and enhancing the utility of opioid drugs in treating pain conditions. We utilize behavioural, biochemical, molecular, and single cell imaging approaches in whole animal models and cell culture systems. This multipronged strategy will enable us to dissect key processes involved in chronic pain, and identify new cellular targets that oppose the pain relieving actions of opioid drugs. The discoveries arising from our work have direct and important benefits for the clinical management of pain conditions in both humans and animals.