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Alastair E. Cribb

Submitted by admin on Mon, 01/25/2010 - 12:17pm
Cribb
Position: 

Dean
Professor, Clinical Pharmacology (CBEM)

Degrees and Board Certification: 

DVM, PhD

Contact Information: 

+1 (403) 220-4570
TRW 2D02
acribb@ucalgary.ca

Biography: 

Alastair Cribb completed his DVM degree at the Western College of Veterinary Medicine in 1984. Following an internship and two years in mixed practice in the Maritimes, he obtained his PhD in pharmacogenetics/clinical pharmacology at the Hospital for Sick Children, University of Toronto in 1991. He followed this with an MRC post-doctoral fellowship at Dalhousie University. He then spent four years in drug safety assessment with Merck & Co. in West Point, PA. In 1996, he joined the Atlantic Veterinary College in Charlottetown as a professor of clinical pharmacology where he spent ten years. He accepted the position of Dean, Faculty of Veterinary Medicine, University of Calgary, in May, 2006. He was previously a CIHR/MRC Scholar, a Canada Research Chair in Comparative Pharmacology and Toxicology, and one of Canada's Top 40 under 40. He was a member of CIHR's Governing Council for five years. Dr. Cribb is a Fellow of the Canadian Academy of Health Sciences.

Teaching : 

Dr. Cribb teaches clinical pharmacology in the DVM program (VM443; VM523) and in the clinical presentations and clinical skills courses.  He also contributes to graduate pharmacology courses.

Research / Scholarly Activities: 

Dr. Cribb's research program focuses on molecular mechanisms of drug and chemical toxicity in animals and humans, and the pharmacogenetic basis of adverse drug reactions and cancer susceptibility. He is particularly interested in the molecular genetics of species and individual differences in response to drugs and chemicals, with an emphasis on idiosyncratic drug reactions.  His work has been funded by the CIHR, the Atlantic Innovation Fund, the Canadian Breast Cancer Research Initiative, and others.

Key words: clinical pharmacology, idiosyncratic drug reactions, molecular toxicology, cytochrome P450, breast cancer

Sample publications (please search Cribb-A* on PubMed for a complete listing): 

Cribb AE, Pohl L, Spielberg SP, Leeder JS.  Patients with delayed onset sulfonamide hypersensitivity reactions have antibodies recognizing endoplasmic reticulum luminal proteins.  Journal of Pharmacology and Experimental Therapeutics, 282: 1064-72, 1997.

McCrea J, Cribb AE, Rushmore T, Osborne B, Gillin L, Lo M-W, Waldman S, Bjornsson T, Spielberg S, Goldberg MR.  Phenotypic and Genotypic Investigations of a Healthy Volunteer Deficient in the Conversion of Losartan to its Active Metabolite, E-3174.  Clin Pharmacol Ther, 64: 348-52, 1999. Gaskill C, Cribb A.  Pancreatitis associated with potassium bromide/phenobarbital combination therapy in epileptic dogs. Can Vet J, 41: 555-558, 2000 Saleh TM, Connell BJ, McQuaid T, Cribb AE.  Estrogen-induced neurochemical and electrophysiological changes in the parabrachial nucleus of the male rat.  Brain Res, 990: 58-65, 2003 McFarlane D, Donaldson M, Cribb AE.  Seasonal and sample handling effects on measurement of plasma α-melanocyte stimulating hormone in horses and ponies.  Am J Vet Res 65: 1463-8, 2004

Gaskill C, Miller LM, Mattoon JS, Hoffmann WE, Burton S,  Gelens H, Ihle S, Miller J, Shaw D, Cribb AE. Liver histopathology and serum alanine aminotransferase and alkaline phosphatase activities in epileptic dogs receiving phenobarbital.  Vet Pathol, 42:  147-160, 2005.

McFarlane D, Dybdal N, Donaldson M, Miller L, Cribb AE. Nitration and increased alpha synuclein expression associated with dopaminergic neurodegeneration in Equine Pituitary Pars Intermedia Dysfunction (PPID).  J of Neuroendocrinology 17:  73-80, 2005. Cribb AE,  Peyrou M, S. Muruganandan, Schneider L.  The endoplasmic reticulum in drug toxicity.  Drug Metabolism Reviews, 37: 405-442, 2005. Cribb AE, Knight J, Dryer D, Guernsey J, Tesch M, Saleh TM.  Role of polymorphic human cytochrome P450 enzymes in estrone oxidation.  Cancer Epidemiology Biomarkers and Prevention 15(3):551-8., 2006. Peyrou M, Cribb AE.   Effect of endoplasmic reticulum stress preconditioning on cytotoxicity of clinically relevant nephrotoxins in renal cell lines.  Toxicol in vitro 21:878-86, 2007. Peyrou M, Cribb AE.  Calpain inhibition but not endoplasmic reticulum stress preconditioning protects rat kidneys from p-aminophenol toxicity. Toxicological Sciences, 99:  338-45, 2007. Peyrou M, Cribb AE.  Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys.  Toxicological Sciences, 99:  346-53, 2007. McConkey SE, Grant DM, Cribb AE.  The role of para-aminophenol in acetaminophen-induced methemoglobinemia in dogs and cats .  J Vet Pharm Ther, 32:  585-595, 2009 Cribb A, Buntain B.  Innovation in veterinary medical education:  the concept of ‘One World, One Health’ in the curriculum of the Faculty of Veterinary Medicine at the University of Calgary.  OEI Scientific and Technical Reviews, 28:  753-762, 2009. Cribb AE, Knight MJ, Guernsey J, Dryer D, Shawwa A, Tesch M, Saleh TM.  Influence of CYP17, catechol-O-methyltransferase, and glutathione transferase M1 genetic polymorphisms on breast cancer risk in women on Prince Edward Island.  Breast J 17: 24-312011

Graduate Program Affiliations : 

Veterinary Medical Sciences

Submitted by admin on Tue, 03/09/2010 - 4:54pm

Medical Sciences

Submitted by admin on Tue, 03/09/2010 - 4:57pm

Ed Stafford

Submitted by lbutcher on Tue, 09/13/2011 - 10:27am
Stafford
Position: 

Senior Director, Operations

Contact Information: 

+1 (403) 210-7021
TRW 2D04
ecstaffo@ucalgary.ca

Jerry Bailey

Submitted by lbutcher on Mon, 11/01/2010 - 11:43am
Bailey
Jerry.jpg
Position: 

Associate Dean, Academic
Professor (Large Animal Surgery)
Veterinary Clinical and Diagnostic Sciences (VCDS)

Contact Information: 

+1 (403) 210-7654
TRW 2E10
jvbailey@ucalgary.ca

John Matyas

Submitted by admin on Tue, 01/26/2010 - 10:55am
Matyas
Position: 

Associate Dean, Graduate Education
Professor (Microscopic Anatomy)
Comparative Biology and Experimental Medicine (CBEM)

Degrees and Board Certification: 

MSc, PhD

Contact Information: 

+1 (403) 220-7189
TRW 2D13
jmatyas@ucalgary.ca

Affiliations : 

McCaig Institute for Bone and Joint Health
Department of Cell Biology & Anatomy, Cumming School of Medicine 
Pathology & Laboratory Medicine, Cumming School of Medicine

 

Biography: 

Dr. Matyas came to UCVM from the Faculty of Medicine at the University of Calgary. He graduated from Cornell University in 1978 with an A.B. in biology. Dr. Matyas went on to study for his M.Sc. at Cornell before coming to the U of C for his Ph.D. under Dr. Cy Frank.

Teaching : 

VETM320        Anatomy & Histology
VETM300        Professional Skills
VETM305        Clinical Skills (Microscopy)
VETM601        Professional Skills (graduate students)

Research / Scholarly Activities: 

Dr. Matyas’ research focuses on joint tissue biomechanics and the causes and treatments of degenerative joint disease.  This includes comparative animal models of joint injury and repair, contribution of stem cells to skeletal healing, functional imaging of connective tissues (cartilage, bone, intervertebral disc) and stereology of connective tissues.  Dr. Matyas also has an interest in chronic joint pain.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=Matyas+JR%5BAuthor%5D

Graduate Program Affiliations : 

Veterinary Medical Sciences

Submitted by admin on Tue, 03/09/2010 - 4:54pm

Biomedical Engineering

Submitted by admin on Tue, 03/09/2010 - 4:55pm

Medical Sciences

Submitted by admin on Tue, 03/09/2010 - 4:57pm

Neuroscience

Submitted by admin on Tue, 03/09/2010 - 4:58pm
Research personnel and trainees : 

Dragana Ponjevic, MSc.
Ganesh Swamy, MD
Nicole Rosin, PhD

Eugene Janzen

Submitted by admin on Tue, 01/26/2010 - 9:50am
Janzen
Position: 

Professor
Production Animal Health (PAH)
Assistant Dean Clinical Practice

Contact Information: 

+1 (403) 210-3972
TRW 2D11
janzene@ucalgary.ca

 

Biography: 

Dr. Janzen received his Doctor of Veterinary Medicine (D.V.M.) in 1972 from the Western College of Veterinary Medicine, Saskatoon, Saskatchewan. Dr. Janzen spent three years practicing in northeastern Alberta before returning to the Western College of Veterinary Medicine on an Alberta-sponsored fellowship to complete a post-graduate degree. Dr. Janzen received an M.V.S. degree from the University of Melbourne, Australia in 1977. In 1977, he accepted a position with the Ambulatory Clinic at the Western College of Veterinary Medicine, Saskatoon, Saskatchewan. In this position, Dr. Janzen has spent his time working with a general interest in beef cattle medicine. Dr. Janzen became associated with Feedlot Health Management Services in 2003.

John Gilleard

Submitted by admin on Mon, 01/25/2010 - 3:49pm
Gilleard
Position: 

Associate Dean, Research
Professor (Parasitology)
Comparative Biology and Experimental Medicine (CBEM)

Degrees and Board Certification: 

BVSc, PhD,  DipACVM, DipEVPC MRCVS

Contact Information: 

+1 (403) 210-6327
TRW 2D10
HS 2557
jsgillea@ucalgary.ca

Biography: 

Dr. Gilleard obtained his BVSc from the Faculty of Veterinary Medicine, University of Liverpool. After three years in general veterinary practice in the UK, he undertook a PhD in Parasitology at the University of Glasgow and then 5 years post-doctoral research in the Wellcome Centre for Molecular Parasitology, at the Department of Genetics, University of Glasgow. Dr. Gilleard was awarded a Wellcome Trust Travel Fellowship in 1998 to spend 2 years in the Faculty of Medicine, University of Calgary before returning to a faculty position at the Faculty of Veterinary Medicine, University of Glasgow, UK. In 2007, he was appointed Professor of Veterinary and Molecular Parasitology at Glasgow before moving to the University of Calgary in 2008 as Professor (Parasitology). He has been Associate Dean Research, in Faculty of Veterinary medicine since 2012.

Teaching : 

Dr. Gilleard teaches parasitology on a variety of courses in the DVM curriculum including VM424 (Veterinary Parasitology), VM405 (Clinical skills II), VETM400 (Clinical Presentations II), VETM 500 (Clinical Presentations III), VM531 (Small ruminants and non-traditional livestock) and VM854 (Equine health)

 

 

Research / Scholarly Activities: 

Dr. Gilleard’s research interests are in the field of drug resistance in parasites.  His research group uses integrated genomic and genetic approaches to elucidate the molecular mechanisms of drug resistance in parasites and population genetic approaches to investigate its emergence and spread. Dr. Gilleard also has an interest in the development of novel diagnostic approaches for parasitic infections and anti-parasitic drug resistance, particularly for cattle parasites.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=Gilleard+JS%5BAuthor%5D

Graduate Program Affiliations : 

Veterinary Medical Sciences

Submitted by admin on Tue, 03/09/2010 - 4:54pm

Biochemistry and Molecular Biology

Submitted by admin on Tue, 03/09/2010 - 4:54pm
Research personnel and trainees : 

James Jian Wang, Laboratory Manager wangji@ucalgary.ca
Russell Avramenko, PhD Student rwavrame@ucalgary.ca
Umer Naveed Chaudhry, PhD Student unchaudh@ucalgary.ca
Dave Curran, PhD Student (co-supervised with James Wasmuth) curran.dave.m@gmail.com
Elizabeth Redman, Post-Doctoral Research Associate libbyredman@hotmail.co.uk
Andrew Rezansoff, PhD Student amrezans@ucalgary.ca
Susan Stasiuk, Post-Doctoral Research Assistant stasiuks@ucalgary.ca
Bradley van Paridon, PhD Student bradley.vanparidon@uleth.ca
Janneke Wit, Post-Doctoral Research Associate jwit@ucalgary.ca
Jocelyn Poissant, Post-Doctoral Researcher Jocelyn.poissant@ucalgary.ca