Research

Research in our lab is focused on understanding the cellular and molecular mechanisms that enable tissue regeneration or conversely promote fibrotic repair following injury.  To do this, we use small and large animal models, transgenesis, high-resolution microscopic imaging, transplantation and cutting-edge high-throughput genomic technologies.  We are particularly intrigued by resident stem cells within skin and brain and how factors like injury, advanced age and the immune system influence their function. Our goal is to leverage these biological insights to inform the development of new therapeutics that restore organ function following injury or disease.