Eduardo Cobo

Research in my laboratory is directed towards elucidating epithelial defensive mechanisms and their involvement in preventing harmful inflammatory responses and controlling infections. I am particularly interested in host defense peptides (HDPs) secreted by neutrophils and epithelial cells, particularly cathelicidins, which are abundantly expressed in mammalians. My aim is to study the role of HDPs in the pathogenesis of disease to decode how the innate system avoids damaging inflammation associated with pathogen persistence. This deeper understanding of the biology of HDPs in the intestine, skin and mammary gland is helpful to develop more effective alternative natural therapeutics against disease.